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Clonality: an R package for testing clonal relatedness of two tumors from the same patient based on their genomic profiles

Summary: If a cancer patient develops multiple tumors, it is sometimes impossible to determine whether these tumors are independent or clonal based solely on pathological characteristics. Investigators have studied how to improve this diagnostic challenge by comparing the presence of loss of heteroz...

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Detalhes bibliográficos
Main Authors: Ostrovnaya, Irina, Seshan, Venkatraman E., Olshen, Adam B., Begg, Colin B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106202/
https://ncbi.nlm.nih.gov/pubmed/21546399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr267
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