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Estimating the Probability of Clonal Relatedness of Pairs of Tumors in Cancer Patients

Next generation sequencing panels are being used increasingly in cancer research to study tumor evolution. A specific statistical challenge is to compare the mutational profiles in different tumors from a patient to determine the strength of evidence that the tumors are clonally related, i.e. derive...

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Detalhes bibliográficos
Publicado no:Biometrics
Main Authors: Mauguen, Audrey, Seshan, Venkatraman E., Ostrovnaya, Irina, Begg, Colin B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677588/
https://ncbi.nlm.nih.gov/pubmed/28482133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12710
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