Phase I Study of Lentiviral-Transduced Chimeric Antigen Receptor-Modified T Cells Recognizing Mesothelin in Advanced Solid Cancers

This phase I study investigated the safety and activity of lentiviral-transduced chimeric antigen receptor (CAR)-modified autologous T cells redirected against mesothelin (CART-meso) in patients with malignant pleural mesothelioma, ovarian carcinoma, and pancreatic ductal adenocarcinoma. Fifteen pat...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Ther
Main Authors: Haas, Andrew R., Tanyi, Janos L., O’Hara, Mark H., Gladney, Whitney L., Lacey, Simon F., Torigian, Drew A., Soulen, Michael C., Tian, Lifeng, McGarvey, Maureen, Nelson, Anne Marie, Farabaugh, Caitlin S., Moon, Edmund, Levine, Bruce L., Melenhorst, J. Joseph, Plesa, Gabriela, June, Carl H., Albelda, Steven M., Beatty, Gregory L.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2019
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838875/
https://ncbi.nlm.nih.gov/pubmed/31420241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.07.015
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki