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Mesothelin as a target for chimeric antigen receptor-modified T cells as anticancer therapy

Mesothelin is a promising target for immune-based therapy, specifically for mesothelioma and pancreatic and ovarian cancers that have high levels of mesothelin expression. Many preclinical and clinical studies that target tumors with high mesothelin expression with antibodies, immunotoxins, antibody...

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Bibliografiske detaljer
Udgivet i:Immunotherapy
Main Authors: O'Hara, Mark, Stashwick, Caitlin, Haas, Andrew R, Tanyi, Janos L
Format: Artigo
Sprog:Inglês
Udgivet: Future Medicine Ltd 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619020/
https://ncbi.nlm.nih.gov/pubmed/26973126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.16.4
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