Mesothelin is a target of chimeric antigen receptor T cells for treating gastric cancer

BACKGROUND: Gastric cancer (GC) is a common cancer in Asia and currently lacks a targeted therapy approach. Mesothelin (MSLN) has been reported to be expressed in GC tissue and could be targeted by chimeric antigen receptor (CAR) T cells. Mesothelin targeting CAR-T has been reported in mesothelioma,...

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I publikationen:J Hematol Oncol
Huvudupphovsmän: Lv, Jiang, Zhao, Ruocong, Wu, Di, Zheng, Diwei, Wu, Zhiping, Shi, Jingxuan, Wei, Xinru, Wu, Qiting, Long, Youguo, Lin, Simiao, Wang, Suna, Wang, Zhi, Li, Yang, Chen, Yantao, He, Qing, Chen, Suimin, Yao, Huihui, Liu, Zixia, Tang, Zhaoyang, Yao, Yao, Pei, Duanqing, Liu, Pentao, Zhang, Xuchao, Zhang, Zhenfeng, Cui, Shuzhong, Chen, Ren, Li, Peng
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2019
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380000/
https://ncbi.nlm.nih.gov/pubmed/30777106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-019-0704-y
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