DNAX-activating protein 10 co-stimulation enhances the anti-tumor efficacy of chimeric antigen receptor T cells

Chimeric antigen receptor (CAR) T cell immunotherapies have shown remarkable efficacy in treating multiple types of hematological malignancies but are not sufficiently effective at treating solid tumors. NKG2D is a strong activating receptor for NK cells and a co-stimulatory receptor for T cells. NK...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Zhao, Ruocong, Cheng, Lin, Jiang, Zhiwu, Wei, Xinru, Li, Baiheng, Wu, Qiting, Wang, Suna, Lin, Simiao, Long, Youguo, Zhang, Xuchao, Wu, Yilong, Du, Xin, Pei, Duanqing, Liu, Pentao, Li, Yangqiu, Cui, Shuzhong, Yao, Yao, Li, Peng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287795/
https://ncbi.nlm.nih.gov/pubmed/30546945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1509173
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