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Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension

Rationale: Pulmonary arterial hypertension (PAH) is a vascular remodeling disease with a poor prognosis and limited therapeutic options. Although the mechanisms contributing to vascular remodeling in PAH are still unclear, several features, including hyperproliferation and resistance to apoptosis of...

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Опубликовано в: :Am J Respir Crit Care Med
Главные авторы: Boucherat, Olivier, Peterlini, Thibaut, Bourgeois, Alice, Nadeau, Valérie, Breuils-Bonnet, Sandra, Boilet-Molez, Stéphanie, Potus, François, Meloche, Jolyane, Chabot, Sophie, Lambert, Caroline, Tremblay, Eve, Chae, Young Chan, Altieri, Dario C., Sutendra, Gopinath, Michelakis, Evangelos D., Paulin, Roxane, Provencher, Steeve, Bonnet, Sébastien
Формат: Artigo
Язык:Inglês
Опубликовано: American Thoracic Society 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6835039/
https://ncbi.nlm.nih.gov/pubmed/29394093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201708-1751OC
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