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Highly Selective Cleavage of TH2-Promoting Cytokines by the Human and the Mouse Mast Cell Tryptases, Indicating a Potent Negative Feedback Loop on TH2 Immunity

Mast cells (MC) are resident tissue cells found primarily at the interphase between tissues and the environment. These evolutionary old cells store large amounts of proteases within cytoplasmic granules, and one of the most abundant of these proteases is tryptase. To look deeper into the question of...

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Pubblicato in:Int J Mol Sci
Autori principali: Fu, Zhirong, Akula, Srinivas, Thorpe, Michael, Hellman, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834136/
https://ncbi.nlm.nih.gov/pubmed/31627390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20205147
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