Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5

Serine proteases constitute the major protein content of mast cell secretory granules. Here we present the extended cleavage specificity of two such proteases from the golden hamster, Mesocricetus auratus. Analysis by phage display technique showed that one of them (HAM1) is a classical chymase with...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Thorpe, Michael, Fu, Zhirong, Albat, Emanuelle, Akula, Srinivas, de Garavilla, Lawrence, Kervinen, Jukka, Hellman, Lars
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283551/
https://ncbi.nlm.nih.gov/pubmed/30521603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207826
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