Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities

Human neutrophils express at least four active serine proteases, cathepsin G, N-elastase, proteinase 3 and neutrophil serine protease 4 (NSP4). They have all been extensively studied due to their importance in neutrophil biology and immunity. However, their extended cleavage specificities have never...

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Publicado en:PLoS One
Main Authors: Thorpe, Michael, Fu, Zhirong, Chahal, Gurdeep, Akula, Srinivas, Kervinen, Jukka, de Garavilla, Lawrence, Hellman, Lars
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898719/
https://ncbi.nlm.nih.gov/pubmed/29652924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195077
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