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Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3—Three Elastases With Similar Primary but Different Extended Specificities and Stability

Serine proteases are major granule constituents of several of the human hematopoietic cell lineages. Four proteolytically active such proteases have been identified in human neutrophils: cathepsin G (hCG), N-elastase (hNE), proteinase 3 (hPR-3), and neutrophil serine protease 4 (hNSP-4). Here we pre...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Fu, Zhirong, Thorpe, Michael, Akula, Srinivas, Chahal, Gurdeep, Hellman, Lars T.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232827/
https://ncbi.nlm.nih.gov/pubmed/30459762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02387
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