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Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3—Three Elastases With Similar Primary but Different Extended Specificities and Stability

Serine proteases are major granule constituents of several of the human hematopoietic cell lineages. Four proteolytically active such proteases have been identified in human neutrophils: cathepsin G (hCG), N-elastase (hNE), proteinase 3 (hPR-3), and neutrophil serine protease 4 (hNSP-4). Here we pre...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Fu, Zhirong, Thorpe, Michael, Akula, Srinivas, Chahal, Gurdeep, Hellman, Lars T.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232827/
https://ncbi.nlm.nih.gov/pubmed/30459762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02387
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