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Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3—Three Elastases With Similar Primary but Different Extended Specificities and Stability

Serine proteases are major granule constituents of several of the human hematopoietic cell lineages. Four proteolytically active such proteases have been identified in human neutrophils: cathepsin G (hCG), N-elastase (hNE), proteinase 3 (hPR-3), and neutrophil serine protease 4 (hNSP-4). Here we pre...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Fu, Zhirong, Thorpe, Michael, Akula, Srinivas, Chahal, Gurdeep, Hellman, Lars T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232827/
https://ncbi.nlm.nih.gov/pubmed/30459762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02387
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