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Highly Selective Cleavage of TH2-Promoting Cytokines by the Human and the Mouse Mast Cell Tryptases, Indicating a Potent Negative Feedback Loop on TH2 Immunity

Mast cells (MC) are resident tissue cells found primarily at the interphase between tissues and the environment. These evolutionary old cells store large amounts of proteases within cytoplasmic granules, and one of the most abundant of these proteases is tryptase. To look deeper into the question of...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Fu, Zhirong, Akula, Srinivas, Thorpe, Michael, Hellman, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834136/
https://ncbi.nlm.nih.gov/pubmed/31627390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20205147
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