Development of Versatile and Flexible Sf9 Packaging Cell Line-Dependent OneBac System for Large-Scale Recombinant Adeno-Associated Virus Production

Recombinant adeno-associated viruses (rAAVs) are excellent vectors for gene delivery. However, current Sf9/Cap-Rep packaging cell line-dependent OneBac systems still lack versatility and flexibility for large-scale production of rAAVs. In this study, we developed an improved OneBac system that inclu...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther Methods
Main Authors: Wu, Yang, Mei, Ting, Jiang, Liangyu, Han, Zengpeng, Dong, Ruping, Yang, Tian, Xu, Fuqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834060/
https://ncbi.nlm.nih.gov/pubmed/31566024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2019.123
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