Highly Variable Pharmacokinetics of Tyramine in Humans and Polymorphisms in OCT1, CYP2D6, and MAO-A

Tyramine, formed by the decarboxylation of tyrosine, is a natural constituent of numerous food products. As an indirect sympathomimetic, it can have potentially dangerous hypertensive effects. In vitro data indicated that the pharmacokinetics of tyramine possibly depend on the organic cation transpo...

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Udgivet i:Front Pharmacol
Main Authors: Rafehi, Muhammad, Faltraco, Frank, Matthaei, Johannes, Prukop, Thomas, Jensen, Ole, Grytzmann, Aileen, Blome, Felix G., Berger, Ralf Günter, Krings, Ulrich, Vormfelde, Stefan V., Tzvetkov, Mladen V., Brockmöller, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831736/
https://ncbi.nlm.nih.gov/pubmed/31736764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01297
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