HAT1 signaling confers to assembly and epigenetic regulation of HBV cccDNA minichromosome

Rationale: Hepatitis B virus (HBV) is a leading cause of liver diseases. HBV covalently closed circular DNA (cccDNA) is a critical obstacle of complete elimination by anti-HBV therapy. HBV cccDNA accumulates in nucleus as a chromatin-like cccDNA minichromosome assembled by histones and non-histones....

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Foilsithe in:Theranostics
Main Authors: Yang, Guang, Feng, Jinyan, Liu, Yunxia, Zhao, Man, Yuan, Ying, Yuan, Hongfeng, Yun, Haolin, Sun, Mingming, Bu, Yanan, Liu, Lei, Liu, Zixian, Niu, Jun-qi, Yin, Ming, Song, Xijun, Miao, Zhenchuan, Lin, Zhongqing, Zhang, Xiaodong
Formáid: Artigo
Teanga:Inglês
Foilsithe: Ivyspring International Publisher 2019
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831306/
https://ncbi.nlm.nih.gov/pubmed/31695772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.37173
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