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Prospects for modulating the CD40/CD40L pathway in the therapy of the hyper-IgM syndrome

The critical role of the CD40/CD40L pathway in B-cell proliferation, immunoglobulin (Ig) isotype switching and germinal center formation has been studied and described extensively in previous literature. Interruption of the CD40/CD40L signal causes hyper-IgM (HIGM) syndrome, which has been classifie...

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Bibliografiska uppgifter
I publikationen:Innate Immun
Huvudupphovsmän: Meng, Xiangxue, Yang, Bin, Suen, Wen-Chen
Materialtyp: Artigo
Språk:Inglês
Publicerad: SAGE Publications 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830763/
https://ncbi.nlm.nih.gov/pubmed/29132233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425917739681
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