Hyper IgM syndrome associated with defective CD40-mediated B cell activation.
Recent studies show that most patients with X-linked hyper IgM syndrome have defects in the gene for CD40 ligand. We evaluated 17 unrelated males suspected of having X-linked hyper IgM syndrome. Activated T cells from 13 of the 17 patients failed to bind a soluble CD40 construct. In these patients,...
Sábháilte in:
| Foilsithe in: | J Clin Invest |
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| Príomhchruthaitheoirí: | , , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
American Society for Clinical Investigation
1994
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| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295267/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7523449/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117476 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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