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Prospects for modulating the CD40/CD40L pathway in the therapy of the hyper-IgM syndrome
The critical role of the CD40/CD40L pathway in B-cell proliferation, immunoglobulin (Ig) isotype switching and germinal center formation has been studied and described extensively in previous literature. Interruption of the CD40/CD40L signal causes hyper-IgM (HIGM) syndrome, which has been classifie...
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| Publicado no: | Innate Immun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6830763/ https://ncbi.nlm.nih.gov/pubmed/29132233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425917739681 |
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