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Androgen Receptor Interaction with Mediator Complex is Enhanced in Castration-Resistant Prostate Cancer by CDK7 Phosphorylation of MED1
In this issue of Cancer Discovery, Rasool et al show that TF11H/CDK7 phosphorylates the MED1 component of the Mediator complex, which enhances its interaction with androgen receptor (AR), and that this phosphorylation is increased in prostate cancer (PCa) that is resistant to castration and enzaluta...
में बचाया:
| में प्रकाशित: | Cancer Discov |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6830511/ https://ncbi.nlm.nih.gov/pubmed/31676563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-19-1028 |
| टैग : |
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