Φορτώνει......
LIS1 regulates cargo-adapter–mediated activation of dynein by overcoming its autoinhibition in vivo
Deficiency of the LIS1 protein causes lissencephaly, a brain developmental disorder. Although LIS1 binds the microtubule motor cytoplasmic dynein and has been linked to dynein function in many experimental systems, its mechanism of action remains unclear. Here, we revealed its function in cargo-adap...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Cell Biol |
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| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Rockefeller University Press
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6829669/ https://ncbi.nlm.nih.gov/pubmed/31562232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201905178 |
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