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p25 of the dynactin complex plays a dual role in cargo binding and dynactin regulation

Cytoplasmic dynein binds its cargoes via the dynactin complex and cargo adapters, and the dynactin pointed-end protein p25 is required for dynein–dynactin binding to the early endosomal dynein adapter HookA (Hook in the fungus Aspergillus nidulans). However, it is unclear whether the HookA–dynein–dy...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Qiu, Rongde, Zhang, Jun, Xiang, Xin
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177580/
https://ncbi.nlm.nih.gov/pubmed/30143531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004000
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