Microtubule binding by dynactin is required for microtubule organization but not cargo transport

Dynactin links cytoplasmic dynein and other motors to cargo and is involved in organizing radial microtubule arrays. The largest subunit of dynactin, p150(glued), binds the dynein intermediate chain and has an N-terminal microtubule-binding domain. To examine the role of microtubule binding by p150(...

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Bibliografiske detaljer
Main Authors: Kim, Hwajin, Ling, Shuo-Chien, Rogers, Gregory C., Kural, Comert, Selvin, Paul R., Rogers, Stephen L., Gelfand, Vladimir I.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2007
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064022/
https://ncbi.nlm.nih.gov/pubmed/17325206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200608128
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