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Identification of a Novel Site in the Tail of Dynein Heavy Chain Important for Dynein Function in Vivo

The minus end-directed microtubule motor cytoplasmic dynein is responsible for the intracellular movements of many organelles, including nuclei and endosomes. The dynein heavy chain contains a C-terminal motor domain and an N-terminal tail domain. The tail binds other dynein subunits and the cargo-i...

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Bibliografske podrobnosti
Main Authors: Qiu, Rongde, Zhang, Jun, Xiang, Xin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554899/
https://ncbi.nlm.nih.gov/pubmed/23212922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.412403
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