TGFβ signaling in germinal center B cells promotes the transition from light zone to dark zone

B cells in germinal centers (GCs) cycle between light zone (LZ) and dark zone (DZ). The cues in the GC microenvironment that regulate the transition from LZ to DZ have not been well characterized. In Peyer’s patches (PPs), transforming growth factor-β (TGFβ) promotes IgA induction in activated B cel...

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Udgivet i:J Exp Med
Main Authors: Albright, Anne R., Kabat, Juraj, Li, Moyi, Raso, Fiona, Reboldi, Andrea, Muppidi, Jagan R.
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829600/
https://ncbi.nlm.nih.gov/pubmed/31506281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181868
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