A carregar...
Germinal Center B Cells Replace Their Antigen Receptors in Dark Zones and Fail Light Zone Entry when Immunoglobulin Gene Mutations are Damaging
Adaptive immunity involves the development of bespoke antibodies in germinal centers (GCs) through immunoglobulin somatic hypermutation (SHM) in GC dark zones (DZs) and clonal selection in light zones (LZs). Accurate selection requires that cells fully replace surface B cell receptors (BCRs) followi...
Na minha lista:
| Publicado no: | Immunity |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6162340/ https://ncbi.nlm.nih.gov/pubmed/30231983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.08.025 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|