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Competition for refuelling rather than cyclic re-entry initiation evident in germinal centers

Antibody affinity maturation occurs in germinal centers (GCs) through iterative rounds of somatic hypermutation and proliferation in dark zones (DZs) and selection in light zones (LZs). GC B cells exit cell cycle a number of hours before entering LZs, therefore continued participation in responses r...

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Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Long, Ziqi, Phillips, Bethan, Radtke, Daniel, Meyer-Hermann, Michael, Bannard, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614495/
https://ncbi.nlm.nih.gov/pubmed/35275753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abm0775
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