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TGFβ signaling in germinal center B cells promotes the transition from light zone to dark zone

B cells in germinal centers (GCs) cycle between light zone (LZ) and dark zone (DZ). The cues in the GC microenvironment that regulate the transition from LZ to DZ have not been well characterized. In Peyer’s patches (PPs), transforming growth factor-β (TGFβ) promotes IgA induction in activated B cel...

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Detalles Bibliográficos
Publicado en:J Exp Med
Main Authors: Albright, Anne R., Kabat, Juraj, Li, Moyi, Raso, Fiona, Reboldi, Andrea, Muppidi, Jagan R.
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829600/
https://ncbi.nlm.nih.gov/pubmed/31506281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181868
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