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The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function

The inner mucus layer (IML) is a critical barrier that protects the colonic epithelium from luminal threats and inflammatory bowel disease. Innate immune signaling is thought to regulate IML formation via goblet cell Nlrp6 inflammasome activity that controls secretion of the mucus structural compone...

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Detalles Bibliográficos
Publicado en:J Exp Med
Main Authors: Volk, Joana K., Nyström, Elisabeth E.L., van der Post, Sjoerd, Abad, Beatriz M., Schroeder, Bjoern O., Johansson, Åsa, Svensson, Frida, Jäverfelt, Sofia, Johansson, Malin E.V., Hansson, Gunnar C., Birchenough, George M.H.
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829596/
https://ncbi.nlm.nih.gov/pubmed/31420376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190679
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