Calcium-activated Chloride Channel Regulator 1 (CLCA1) Controls Mucus Expansion in Colon by Proteolytic Activity

Many epithelial surfaces of the body are covered with protective mucus, and disrupted mucus homeostasis is coupled to diseases such as ulcerative colitis, helminth infection, cystic fibrosis, and chronic obstructive lung disease. However, little is known how a balanced mucus system is maintained. By...

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Библиографические подробности
Опубликовано в: :EBioMedicine
Главные авторы: Nyström, Elisabeth E.L., Birchenough, George M.H., van der Post, Sjoerd, Arike, Liisa, Gruber, Achim D., Hansson, Gunnar C., Johansson, Malin E.V.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2018
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085540/
https://ncbi.nlm.nih.gov/pubmed/29885864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.05.031
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