Calcium-activated Chloride Channel Regulator 1 (CLCA1) Controls Mucus Expansion in Colon by Proteolytic Activity

Many epithelial surfaces of the body are covered with protective mucus, and disrupted mucus homeostasis is coupled to diseases such as ulcerative colitis, helminth infection, cystic fibrosis, and chronic obstructive lung disease. However, little is known how a balanced mucus system is maintained. By...

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Detalles Bibliográficos
Publicado en:EBioMedicine
Main Authors: Nyström, Elisabeth E.L., Birchenough, George M.H., van der Post, Sjoerd, Arike, Liisa, Gruber, Achim D., Hansson, Gunnar C., Johansson, Malin E.V.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2018
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085540/
https://ncbi.nlm.nih.gov/pubmed/29885864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.05.031
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