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The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function
The inner mucus layer (IML) is a critical barrier that protects the colonic epithelium from luminal threats and inflammatory bowel disease. Innate immune signaling is thought to regulate IML formation via goblet cell Nlrp6 inflammasome activity that controls secretion of the mucus structural compone...
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| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6829596/ https://ncbi.nlm.nih.gov/pubmed/31420376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190679 |
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