The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function

The inner mucus layer (IML) is a critical barrier that protects the colonic epithelium from luminal threats and inflammatory bowel disease. Innate immune signaling is thought to regulate IML formation via goblet cell Nlrp6 inflammasome activity that controls secretion of the mucus structural compone...

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Detaylı Bibliyografya
Yayımlandı:J Exp Med
Asıl Yazarlar: Volk, Joana K., Nyström, Elisabeth E.L., van der Post, Sjoerd, Abad, Beatriz M., Schroeder, Bjoern O., Johansson, Åsa, Svensson, Frida, Jäverfelt, Sofia, Johansson, Malin E.V., Hansson, Gunnar C., Birchenough, George M.H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Rockefeller University Press 2019
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829596/
https://ncbi.nlm.nih.gov/pubmed/31420376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190679
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