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Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model
Chronic activation of brain innate immunity is a prominent feature of Alzheimer’s disease (AD) and primary tauopathies. However, to what degree innate immunity contributes to neurodegeneration as compared with pathological protein-induced neurotoxicity, and the requirement of a particular glial cell...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6829593/ https://ncbi.nlm.nih.gov/pubmed/31601677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190980 |
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