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Glial contributions to neurodegeneration in tauopathies

Abstract Tauopathies are a broad set of neurodegenerative dementias characterized by aggregation of the tau protein into filamentous inclusions that can be found in neurons and glial cells. Activated microglia, astrocytes and elevated levels of proinflammatory molecules are also pathological hallmar...

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Bibliographic Details
Main Authors: Cheryl E. G. Leyns, David M. Holtzman
Format: Artigo
Language:Inglês
Published: BMC 2017-06-01
Series:Molecular Neurodegeneration
Subjects:
Tau
Online Access:http://link.springer.com/article/10.1186/s13024-017-0192-x
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