Regulation of Skn7-dependent, oxidative stress-induced genes by the RNA polymerase II-CTD phosphatase, Fcp1, and Mediator kinase subunit, Cdk8, in yeast

Fcp1 is a protein phosphatase that facilitates transcription elongation and termination by dephosphorylating the C-terminal domain of RNA polymerase II. High-throughput genetic screening and gene expression profiling of fcp1 mutants revealed a novel connection to Cdk8, the Mediator complex kinase su...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Aristizabal, Maria J., Dever, Kristy, Negri, Gian Luca, Shen, Mary, Hawe, Nicole, Benschop, Joris J., Holstege, Frank C. P., Krogan, Nevan J., Sadowski, Ivan, Kobor, Michael S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Gene Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827322/
https://ncbi.nlm.nih.gov/pubmed/31506296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008515
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares