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The structure of Fcp1, an essential RNA polymerase II CTD phosphatase

Kinases and phosphatases regulate mRNA synthesis and processing by phosphorylating and dephosphorylating the C-terminal domain (CTD) of the largest subunit of RNA polymerase II. Fcp1 is an essential CTD phosphatase that preferentially hydrolyzes Ser2-PO(4) of the tandem YSPTSPS CTD heptad array. Fcp...

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Detalhes bibliográficos
Main Authors: Ghosh, Agnidipta, Shuman, Stewart, Lima, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645342/
https://ncbi.nlm.nih.gov/pubmed/19026779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.09.021
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