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Structural insights to how mammalian capping enzyme reads the CTD code

Physical interaction between the phosphorylated RNA polymerase II carboxyl-terminal domain (CTD) and cellular capping enzymes is required for efficient formation of the 5' mRNA cap, the first modification of nascent mRNA. Here we report the crystal structure of the RNA guanylyltransferase compo...

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Detalhes bibliográficos
Main Authors: Ghosh, Agnidipta, Shuman, Stewart, Lima, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142331/
https://ncbi.nlm.nih.gov/pubmed/21683636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.06.001
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