How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes

Interactions between RNA guanylyltransferase (GTase) and the C-terminal domain (CTD) repeats of RNA polymerase II (Pol2) and elongation factor Spt5 are thought to orchestrate cotranscriptional capping of nascent mRNAs. The crystal structure of a fission yeast GTase•Pol2 CTD complex reveals a unique...

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Bibliographic Details
Main Authors: Doamekpor, Selom K., Sanchez, Ana M., Schwer, Beate, Shuman, Stewart, Lima, Christopher D.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2014
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066402/
https://ncbi.nlm.nih.gov/pubmed/24939935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.242768.114
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