Fcp1 directly recognizes the C-terminal domain (CTD) and interacts with a site on RNA polymerase II distinct from the CTD

Fcp1 is an essential protein phosphatase that hydrolyzes phosphoserines within the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II). Fcp1 plays a major role in the regulation of CTD phosphorylation and, hence, critically influences the function of Pol II throughout the tr...

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Bibliografiske detaljer
Main Authors: Suh, Man-Hee, Ye, Ping, Zhang, Mincheng, Hausmann, Stéphane, Shuman, Stewart, Gnatt, Averell L., Fu, Jianhua
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297677/
https://ncbi.nlm.nih.gov/pubmed/16301539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507987102
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