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The RNAPII-CTD Maintains Genome Integrity through Inhibition of Retrotransposon Gene Expression and Transposition

RNA polymerase II (RNAPII) contains a unique C-terminal domain that is composed of heptapeptide repeats and which plays important regulatory roles during gene expression. RNAPII is responsible for the transcription of most protein-coding genes, a subset of non-coding genes, and retrotransposons. Ret...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Aristizabal, Maria J., Negri, Gian Luca, Kobor, Michael S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619828/
https://ncbi.nlm.nih.gov/pubmed/26496706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005608
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