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Retrotransposon overdose and genome integrity

Yeast and mammalian genomes are replete with nearly identical copies of long dispersed repeats in the form of retrotransposons. Mechanisms clearly exist to maintain genome structure in the face of potential rearrangement between the dispersed repeats, but the nature of this machinery is poorly under...

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Autors principals: Scheifele, Lisa Z., Cost, Gregory J., Zupancic, Margaret L., Caputo, Emerita M., Boeke, Jef D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728997/
https://ncbi.nlm.nih.gov/pubmed/19666515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906552106
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