Llwytho...
RecQL4 tethering on the pre-replicative complex induces unscheduled origin activation and replication stress in human cells
Sequential activation of DNA replication origins is precisely programmed and critical to maintaining genome stability. RecQL4, a member of the conserved RecQ family of helicases, plays an essential role in the initiation of DNA replication in mammalian cells. Here, we showed that RecQL4 protein teth...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Biol Chem |
|---|---|
| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Society for Biochemistry and Molecular Biology
2019
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6827294/ https://ncbi.nlm.nih.gov/pubmed/31519754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009996 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|