Assembly of the Cdc45-Mcm2–7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins

In eukaryotes, the activation of the prereplicative complex and assembly of an active DNA unwinding complex are critical but poorly understood steps required for the initiation of DNA replication. In this report, we have used bimolecular fluorescence complementation assays in HeLa cells to examine t...

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Detalles Bibliográficos
Main Authors: Im, Jun-Sub, Ki, Sang-Hee, Farina, Andrea, Jung, Dong-Soo, Hurwitz, Jerard, Lee, Joon-Kyu
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747170/
https://ncbi.nlm.nih.gov/pubmed/19805216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908039106
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