RecQL4 is required for the association of Mcm10 and Ctf4 with replication origins in human cells

Though RecQL4 was shown to be essential for the initiation of DNA replication in mammalian cells, its role in initiation is poorly understood. Here, we show that RecQL4 is required for the origin binding of Mcm10 and Ctf4, and their physical interactions and association with replication origins are...

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Détails bibliographiques
Publié dans:Cell Cycle
Auteurs principaux: Im, Jun-Sub, Park, Soon-Young, Cho, Won-Ho, Bae, Sung-Ho, Hurwitz, Jerard, Lee, Joon-Kyu
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2015
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Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612657/
https://ncbi.nlm.nih.gov/pubmed/25602958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1007001
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