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Assembly of the Cdc45-Mcm2–7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins

In eukaryotes, the activation of the prereplicative complex and assembly of an active DNA unwinding complex are critical but poorly understood steps required for the initiation of DNA replication. In this report, we have used bimolecular fluorescence complementation assays in HeLa cells to examine t...

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Detalhes bibliográficos
Main Authors: Im, Jun-Sub, Ki, Sang-Hee, Farina, Andrea, Jung, Dong-Soo, Hurwitz, Jerard, Lee, Joon-Kyu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747170/
https://ncbi.nlm.nih.gov/pubmed/19805216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908039106
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