Nascent Lung Organoids Reveal Epithelium- and Bone Morphogenetic Protein–mediated Suppression of Fibroblast Activation

Reciprocal epithelial–mesenchymal interactions are pivotal in lung development, homeostasis, injury, and repair. Organoids have been used to investigate such interactions, but with a major focus on epithelial responses to mesenchyme and less attention to epithelial effects on mesenchyme. In the pres...

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Bibliografiske detaljer
Udgivet i:Am J Respir Cell Mol Biol
Main Authors: Tan, Qi, Ma, Xiao Yin, Liu, Wei, Meridew, Jeffrey A., Jones, Dakota L., Haak, Andrew J., Sicard, Delphine, Ligresti, Giovanni, Tschumperlin, Daniel J.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2019
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827068/
https://ncbi.nlm.nih.gov/pubmed/31050552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0390OC
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