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Gene-Specific Targeting of DNA Methylation in the Mammalian Genome
DNA methylation is the most widely-studied epigenetic modification, playing a critical role in the regulation of gene expression. Dysregulation of DNA methylation is implicated in the pathogenesis of numerous diseases. For example, aberrant DNA methylation in promoter regions of tumor-suppressor gen...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6827012/ https://ncbi.nlm.nih.gov/pubmed/31600992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101515 |
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