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The molecular basis of LST-1 self-renewal activity and its control of stem cell pool size
PUF RNA-binding proteins have diverse roles in animal development, with a broadly conserved role in stem cells. Two paradigmatic PUF proteins, FBF-1 and FBF-2, promote both self-renewal and differentiation in the C. elegans germline. The LST-1 protein is a pivotal regulator of self-renewal and is on...
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| Veröffentlicht in: | Development |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists Ltd
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6826033/ https://ncbi.nlm.nih.gov/pubmed/31515205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.181644 |
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