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A PUF Hub Drives Self-Renewal in Caenorhabditis elegans Germline Stem Cells

Stem cell regulation relies on extrinsic signaling from a niche plus intrinsic factors that respond and drive self-renewal within stem cells. A priori, loss of niche signaling and loss of the intrinsic self-renewal factors might be expected to have equivalent stem cell defects. Yet this simple predi...

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Vydáno v:Genetics
Hlavní autoři: Haupt, Kimberly A., Law, Kimberley T., Enright, Amy L., Kanzler, Charlotte R., Shin, Heaji, Wickens, Marvin, Kimble, Judith
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944405/
https://ncbi.nlm.nih.gov/pubmed/31740451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302772
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